she was subsequently attacked and bitten by
the animal on her left upper thigh. Her husband shot the animal to
dislodge it from her thigh. The bite resulted in a jagged 3 inch wound,
and the woman was treated at a local hospital. The animal was diagnosed as
rabid by the direct immunofluorescent antibody test on a brain specimen,
from which rabies virus was also isolated. The woman received rabies
postexposure prophylaxis.
Editorial Note: This is the first report of rabies in a javelina. Bites by
javelina are most likely to occur while the animals are being sought as
game.
Almost all wildlife rabies in the United States occurs among skunk,
raccoon, bat, and fox species (in decreasing frequency of reported cases);
however, the disease is occasionally found in an unexpected host. The
origin of rabies in these animals can be investigated by typing the virus
with a panel of monoclonal antibodies (mabs) to nucleocapsid proteins (1).
On the basis of nucleocapsid reactivity with a panel of mabs, five
antigenically distinct groups of rabies viruses can be formed from
isolates collected from the major terrestrial wildlife rabies enzootic
areas of the United States. These five antigenically distinct groups
comprise isolates collected from: (1) skunk rabies areas of California and
the north central United States and gray fox rabies areas of central
Texas; (2) skunk rabies areas of the south central United States; (3)
raccoon rabies areas of the mid-Atlantic and southeastern United States;
(4) red fox rabies areas of the northeast United States; and (5) gray fox
rabies areas of Arizona.
There are two separate enzootic hosts for rabies in Arizona, the striped
skunk and the gray fox. Virus isolates from these two species can easily
be distinguished with mabs. Rabies virus from the javelina was identical
to that found in rabid gray foxes in Arizona, suggesting that the
infection in the javelina was the result of spillover from enzootic
disease in foxes. The reaction pattern found in virus isolates from foxes
in Arizona is unique among over 300 rabies isolates collected from
terrestrial mammals elsewhere in the United States. Moreover, the virus
strains in foxes and skunks in Arizona are different from each other, even
when infected animals of both species are found in the same area. Fox
virus isolates from Texas also differ in their reactivity pattern from
skunks in Texas, even when isolates from both species are collected in the
same county. This observation is unique to Arizona and Texas.
This case emphasizes the importance of assessing every mammal bite
individually for the possibility of rabies. After the bite of a wild
animal, the decision to administer postexposure rabies prophylaxis is
based on the results of fluorescent antibody examination of the animal
brain, the status of rabies activity in the area where the bite occurred,
and the species of biting animal.